E-mail:yanwang@bnu.edu.cn
个人主页:暂无教育背景:
2005.09 - 2010.12 周口师范学院,生物学,学士
2011.09 - 2014.06 河南农业大学,植物学,硕士
2014.09 - 2019.01 中国科学院大学,发育生物学,博士
工作经历:
2019.02 - 2026.04 美国杜克大学,生物系,博士后
2026.06至今 北京师范大学,生命科学学院,教授
2025年获得国家自然科学基金优秀青年科学基金项目(海外)
本课题组聚焦蛋白糖基化修饰(O/N-糖基化)响应环境信号并调控植物发育可塑性与逆境适应性的分子机制。综合运用生物化学、分子生物学、遗传学、细胞生物学及多组学等研究手段,重点开展以下研究方向:
1. 解析糖基化修饰响应环境信号调控植物生长发育可塑性的分子机制;
2. 系统阐明糖基化修饰介导植物逆境适应与抗逆韧性的调控网络;
3. 揭示作物中糖基化修饰的生物学功能及其在作物遗传改良中的应用潜力。
课题组致力于探索植物环境适应与发育调控的新机制,解析其在植物发育与环境响应中的调控机制,为作物高产、稳产及抗逆育种提供理论基础和潜在靶标。
课题组长期招收具有多组学、生物化学、分子生物学、植物学、生物信息学等相关背景的本科生、研究生和博士后。特别欢迎对蛋白翻译后修饰、植物信号转导及环境适应机制研究感兴趣的同学和青年学者加入。
1. Dahal P#, Wang Y#, Hu J, Park J, Forker K, Zhang Z-L, Sharma K, Borgnia MJ, Sun T-P*, Zhou P*. Structural insights into proteolysis-dependent and -independent suppression of the master regulator DELLA by the gibberellin receptor. Proc Natl Acad Sci U S A. (2025) 12;122(32):e2511012122.
2. Wang Y, Kelley S, Zentella R, Hu J, Wei H, Wang L, Shabanowitz J, Hunt DF, Sun T-P*. The O-Fucosyltransferase SPINDLY Attenuates Auxin-Induced Fruit Growth by Inhibiting ARF6 and ARF8 binding to Coactivator Mediator Complex in Arabidopsis. Nature Communications. (2025) 16, 3965.
3. Kumar S#, Wang Y#, Zhou Y, Dillard L, Li F-W, Sciandra CA, Sui N, Zentella R, Zahn E, Shabanowitz J, Hunt DF, Borgnia MJ, Bartesaghi A, Sun T-P*, Zhou P*. Structure and dynamics of the Arabidopsis O-fucosyltransferase SPINDLY. Nature Communications. (2023) 14 (1), 1538.
4. Zentella R#, Wang Y#, Zahn E, Hu J, Jiang L, Shabanowitz J, Hunt DF, Sun T-P*. SPINDLY O-Fucosylates Nuclear and Cytoplasmic Proteins Involved in Diverse Cellular Processes in Plants. Plant Physiology. (2023) 191(3), 1546-1560.
5. Wang Y#, Su C#, Yu Y#, He Y , Wei H, Li N, Li H, Duan J, Li B, Li J, Davis S, Wang L*. TIME FOR COFFEE regulates phytochrome A-mediated hypocotyl growth through dawn-phased signaling. The Plant Cell. (2022) 8 (34), 2907-2024.
6. Wang Y, Zhuang L, and Wang L*. Uncover the Nuclear Proteomic Landscape with Enriched Nuclei Followed by Label-Free Quantitative Mass Spectrometry. Plant Photomorphogenesis: Methods and Protocols, Methods in Molecular Biology. (2021) vol. 2297.
7. Su C, Wang Y, Yu Y, He Y, Wang L*. Coordinative regulation of plants growth and development by light and circadian clock. aBIOTECH, (2021) 176–189.
8. Wang Y, He Y, Su C, Zentella R, Sun T-P and Wang L*. Nuclear Localized O-Fucosyltransferase SPY Facilitates PRR5 Proteolysis to Fine-Tune the Pace of Arabidopsis Circadian Clock. Molecular Plant. (2020) 13(3): 446-458.(Cover letter)
9. Wang Y#, Qin YM#, Li B, Zhang Y, Wang L*. Attenuated TOR signaling lengthens circadian period in Arabidopsis. Plant Signaling & Behavior. (2020) 2: e1710935. (#: Equal contribution)
10. Li N, Zhang Y, He Y, Wang Y, Wang L*. Pseudo Response Regulators Regulate Photoperiodic Hypocotyl Growth by Repressing PIF4/5 Transcription. Plant Physiology. (2020) 183(2):686-699.
11. Li B#, Wang Y#, Zhang Y, Tian W, Chong K, Jang J-C , Wang L*. PRRs Positively Regulates TOR Signaling Mediated Root Cell Proliferation by Repressing TANDEM ZINC FINGER 1 in Arabidopsis. Nucleic Acids Res. (2019) 47(10): 5001–5015.
12. Wang Y, Zhang Y, and Wang L*. Cross Regulatory Network Between Circadian Clock and Leaf Senescence is Emerging in Higher Plants. Frontiers in Plant Science. (2018) 9: 700.
13. Zhang Y, Wang Y, Wei H, Li N, Tian W, Chong K, Wang L*. Circadian Evening Complex Represses Jasmonate-Induced Leaf Senescence in Arabidopsis. Molecular Plant. (2018) 11(2): 326-337. (Cover letter)
14. Wang Y, Xu K, Zhang Y, Liu K, Zhang F, Zhang J, Tan G, and Li C*. First Report of Powdery Mildew Caused by Erysiphe heraclei on Carrot in Central China. Plant Disease. (2014) 98:277.
(#: Equal contribution; *: Corresponding author)