2015年于南京大学生命科学学院获学士学位；2021年于中科院遗传与发育生物学研究所获得博士学位，师从田烨研究员，2021年-2025年留组进行博士后阶段的训练。专注于“神经-外周组织互作”“应激反应跨代遗传”两大特色研究方向。以第一作者(含共一)在Cell, Nature Cell Biology, Nature Communications, Cell Reports等杂志发表研究论文。2025年起加入北京师范大学生命科学学院。主持国家自然科学基金面上项目（2025-2028），青年项目（2023-2024）；入选国家博士后创新人才支持计划及全国年度10人“未来女科学家计划”，获中国科学院优秀博士论文、院长特别奖等荣誉。

本课题组围绕线粒体功能衰退这一衰老核心驱动力，主要探索以下两个方向：

1.衰老过程中神经元线粒体损伤如何影响外周代谢稳态。

2.开发线粒体功能修复新技术。

(# Co-first author; * Corresponding author)

Wang, Z. ^#, Zhang, Q. ^#, Jiang, Y., Zhou, J., and Tian, Y.* (2024). ASI-RIM neuronal axis regulates systemic mitochondrial stress response via TGF-β signaling cascade. Nature Communications. 15, 8997.

张茜, 王子豪, 田烨, (2023). 跨组织线粒体应激信号交流调控机体衰老研究进展. 遗传 45, 187–197.

Zhang, Q., and Tian, Y.* (2022). Molecular Insights into the Transgenerational Inheritance of Stress Memory. Journal of Genetics and Genomics, 49, 89-95.

Zhang, Q., Wang, Z., Zhang, W., Wen, Q., Li, X., Zhou, J., Wu, X., Guo, Y., Liu, Y., Wei, C., Qian, W., and Tian, Y.* (2021). The memory of neuronal mitochondrial stress is inherited transgenerationally via elevated mitochondrial DNA levels. Nature Cell Biology. 23, 870–880. Cover article.

Rong, B. ^#, Zhang, Q. ^#, Wan, J., Xing, S., Dai, R., Li, Y., Cai, J., Xie, J., Song, Y., Chen, J., Zhang, L., Yan, G., Zhang, W., Gao, H., Han, J., Qu, Q., Ma, H. *, Tian, Y. *, and Lan, F. * (2020). Ribosome 18S m6A methyltransferase METTL5 promotes translation initiation and breast cancer cell growth. Cell Reports. 33, 108544.

Zhang, Q.^#, Wu, X.^#, Chen, P.^#, Liu, L., Xin, N., Tian, Y.*, and Dillin A.* (2018). Mitochondrial unfolded protein response is mediated cell-non-autonomously by retromer-dependent Wnt signaling. Cell, 174, 870-883.e17.

Liu, Y. ^#, Zhou, J.^#, Zhang, N., Wu, X., Zhang, Q., Zhang, W., Li, X., and Tian, Y.* (2022). Two Sensory Neurons Coordinate the Systemic Mitochondrial Stress Response via GPCR Signaling in C. elegans. Developmental Cell, 57, 2469-2482.e5.

Li, X., Li, J., Zhu, D., Zhang, N., Hao, X., Zhang, W., Zhang, Q., Liu, Y., Wu, X., and Tian, Y.* (2022). Protein Disulfide Isomerase PDI-6 Assists Wnt Secretion to Coordinate Inter-tissue UPR^mt and Lifespan. Cell Reports, 39, 110931.