1992年9月至1996年7月,北京师范大学数学系计算机专业本科生,获理学学士;2005年9月至2008年7月,北京师范大学生命与科学学院生物信息学研究生,获理学硕士;2008年9月至2011年7月,北京师范大学生命与科学学院生物信息学研究生,获理学博士。为本科生和研究生开设《程序设计基础》 和《生物信息学》等课程。
感兴趣的问题是基因组中信号的识别及其功能注释,具体研究内容:
■可变剪切信号的识别及其功能注释
■物种间保守序列的识别及其功能注释
■遗传变异的识别及其功能注释
■甲基化修饰位点的预测
■ Zhang Q, Cao L, H. Song, K. Lin, and E. L. Pang*.2023. MkcDBGAS: a reference-free approach to identify comprehensive alternative splicing events in a transcriptome. Brief Bioinform. 24:bbad367
■ Song, H., Q. Wang, Z. Zhang, K. Lin, and E. L. Pang*. 2023. Identification of clade-wide putative cis-regulatory elements from conserved non-coding sequences in Cucurbitaceae genomes. Horticulture Research 10:uhad038.
■ Yu, R.-M., N. Zhang, B.-W. Zhang, Y. Liang, X.-X. Pang, L. Cao, Y.-D. Chen, W.-P. Zhang, Y. Yang, D.-Y. Zhang*, E. L. Pang*, and W.-N. Bai*. 2023. Genomic insights into biased allele loss and increased gene numbers after genome duplication in autotetraploid Cyclocarya paliurus. BMC Biology 21:168.
■ Cao, L., Q. Zhang, H. Song, K. Lin, and E. L. Pang*. 2022. DeepASmRNA: Reference-free prediction of alternative splicing events with a scalable and interpretable deep learning model. iScience 25:105345.
■ Zhang, W. P., L. Cao, X. R. Lin, Y. M. Ding, Y. Liang, D. Y. Zhang, E. L. Pang*, S. S. Renner*, and W. N. Bai*. 2022. Dead-end hybridization in walnut trees revealed by large-scale genomic sequence data. Mol Biol Evol 39:msab308.
■ Lin, X., N. Zhang, H. Song, K. Lin, and E. L. Pang*. 2022. Population-specific, recent positive selection signatures in cultivated Cucumis sativus L. (cucumber). G3 (Bethesda) 12.
■ Chen, Y., Y. Miao, W. Bai, K. Lin, and E. L. Pang*. 2022. Characteristics and potential functional effects of long insertions in Asian butternuts. BMC Genomics 23:732.
■ Yan, X., D. Bai, H. Song, K. Lin, and E. L. Pang*. 2021. Alternative splicing during fruit development among fleshy fruits. BMC Genomics 22:762.
■ Sun, Y., Q. Zhang, B. Liu, K. Lin, Z. Zhang, and E. L. Pang*. 2020. CuAS: a database of annotated transcripts generated by alternative splicing in cucumbers. BMC Plant Biol 20:119.
■ Sun, Y., H. Hou, H. Song, K. Lin, Z. Zhang, J. Hu, and E. L. Pang*. 2018. The comparison of alternative splicing among the multiple tissues in cucumber. BMC Plant Biol 18:5.
■ Song, H., K. Lin, J. Hu, and E. L. Pang*. 2018. An updated functional annotation of protein-coding genes in the cucumber genome. Front Plant Sci 9:325.
■ E. L. Pang*, Y. Hao, Y. Sun, and K. Lin. 2016. Differential variation patterns between hubs and bottlenecks in human protein-protein interaction networks. BMC Evol Biol 16:260.